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小鼠 Ly108/SLAMF6 基因ORF全长cDNA克隆(表达载体), C-His 标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
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11945-H08H-50
11945-H08H-100
50 µg 
100 µg 
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表达宿主: Human Cells  
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11945-H02H-50
11945-H02H-100
50 µg 
100 µg 
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表达宿主: Human Cells  
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11945-HCCH-50
11945-HCCH-100
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100 µg 
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描述: Active  
表达宿主: Human Cells  
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50275-M08H-50
50275-M08H-100
50 µg 
100 µg 
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反应性: Human  
应用 : 
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11945-R002-F-25
11945-R002-F-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
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11945-R002-P-25
11945-R002-P-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
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11945-R105-F-25
11945-R105-F-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
  • Slide 1
11945-R105-P-25
11945-R105-P-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
  • Slide 1
11945-R002-A-25
11945-R002-A-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
  • Slide 1
11945-R105-A-25
11945-R105-A-100
25 Test 
100 Tests 
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反应性: Human  
应用 : 
  • Slide 1
11945-R002-50
11945-R002-100
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100 µg 
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反应性: Human  
应用 : 
    11945-MM10-50
    11945-MM10-200
    11945-MM10-100
    11945-MM10-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
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    反应性: Human  
    应用 : ELISA  
      11945-RP01-400
      11945-RP01-200
      11945-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        11945-R110-50
        11945-R110-100
        11945-R110-1
        50 µg 
        100 µg 
        1 mg 
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        反应性: Human  
        应用 : ELISA  
          11945-RP02-50
          11945-RP02-200
          11945-RP02-100
          50 µg 
          200 µg 
          100 µg 
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          反应性: Human  
          应用 : ELISA  
            11945-MM08-50
            11945-MM08-200
            11945-MM08-100
            50 µg 
            200 µg 
            100 µg 
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            反应性: Human  
            应用 : IHC-P  
            • Slide 1
            • Slide 1
            • Slide 1
            11945-R005-50
            11945-R005-100
            50 µg 
            100 µg 
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            反应性: Human  
            应用 : 
            • Slide 1
            11945-R105-50
            11945-R105-100
            50 µg 
            100 µg 
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            反应性: Mouse  
            应用 : ELISA  
              50275-RP01-200
              50275-RP01-100
              200 µg 
              100 µg 
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              反应性: Mouse  
              应用 : ELISA  
                50275-RP02-50
                50275-RP02-200
                50275-RP02-100
                50 µg 
                200 µg 
                100 µg 
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                Ly108/SLAMF6 cDNARelated Products

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                Ly108/SLAMF6 cdna-clone 研究背景

                SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.

                小鼠 Ly108/SLAMF6 cdna-clone 参考资料
              • Gray CW. et al., 2000, Eur J Biochem. 267 (18): 5699-710.
              • Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
              • Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
              • Claus M. et al., 2007, Front Biosci. 13: 956-65.
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