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人 PCSK9 ORF mammalian expression plasmid, N-His 标签

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表达宿主: Human Cells  
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10594-H08H1-50
10594-H08H1-10
50 µg 
10 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
10594-H08H-50
10594-H08H-20
10594-H08H-10
50 µg 
20 µg 
10 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
50251-M08H-20
50251-M08H-10
20 µg 
10 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
80005-R08H-20
80005-R08H-10
20 µg 
10 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
11054-K08H-20
11054-K08H-10
20 µg 
10 µg 
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反应性: Human  
应用 : ELISA  IHC-P  
  • Slide 1
10594-T24-50
10594-T24-200
10594-T24-100
50 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    10594-MM01-50
    10594-MM01-200
    10594-MM01-100
    50 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      10594-RP02-400
      10594-RP02-200
      10594-RP02-100
      400 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        10594-RM03-50
        10594-RM03-100
        50 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  
          10594-T16-50
          10594-T16-200
          10594-T16-100
          50 µg 
          200 µg 
          100 µg 
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          反应性: Human  
          应用 : ELISA  
            10594-RP01-400
            10594-RP01-200
            10594-RP01-100
            400 µg 
            200 µg 
            100 µg 
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            反应性: Mouse  
            应用 : ELISA  
              50251-RP02-50
              50251-RP02-200
              50251-RP02-100
              50 µg 
              200 µg 
              100 µg 
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              反应性: Mouse  
              应用 : 
              • Slide 1
              • Slide 1
              • Slide 1
              50251-T26-50
              50251-T26-200
              50251-T26-100
              50 µg 
              200 µg 
              100 µg 
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              反应性: Mouse  
              应用 : ELISA  
                50251-RP01-400
                50251-RP01-200
                50251-RP01-100
                400 µg 
                200 µg 
                100 µg 
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                反应性: Mouse  
                应用 : ELISA  
                  50251-R106-50
                  50251-R106-100
                  50 µg 
                  100 µg 
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                  反应性: Mouse  
                  应用 : 
                    50251-R214-50
                    50251-R214-100
                    50251-R214-1
                    50 µg 
                    100 µg 
                    1 mg 
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                    反应性: Rat  
                    应用 : 
                      80005-MM06-50
                      80005-MM06-200
                      80005-MM06-100
                      80005-MM06-1
                      50 µg 
                      200 µg 
                      100 µg 
                      1 mg 
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                      反应性: Rat  
                      应用 : ELISA  
                        80005-MM03-50
                        80005-MM03-200
                        80005-MM03-100
                        50 µg 
                        200 µg 
                        100 µg 
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                        反应性: Rat  
                        应用 : ELISA  
                          80005-RP01-400
                          80005-RP01-200
                          80005-RP01-100
                          400 µg 
                          200 µg 
                          100 µg 
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                          反应性: Rat  
                          应用 : 
                            80005-R007-50
                            80005-R007-100
                            80005-R007-1
                            50 µg 
                            100 µg 
                            1 mg 
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                            反应性: Rat  
                            应用 : ELISA  
                              80005-RP02-50
                              80005-RP02-200
                              80005-RP02-100
                              50 µg 
                              200 µg 
                              100 µg 
                              Add to Cart
                              反应性: Rat  
                              应用 : IHC-P  
                              • Slide 1
                              80005-MM04-50
                              80005-MM04-200
                              80005-MM04-100
                              50 µg 
                              200 µg 
                              100 µg 
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                              PCSK9/NARC1 ELISA配对抗体

                              检测限: 47 pg/ml
                              SEK80005-5
                              SEK80005-15
                              5 Plates 
                              15 Plates 
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                              检测限: 62.5 pg/ml
                              SEK50251-5
                              SEK50251-15
                              5 Plates 
                              15 Plates 
                              Add to Cart

                              PCSK9/NARC1 cDNARelated Products

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                              PCSK9/NARC1 cdna-clone 研究背景

                              Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

                              References

                               PCSK9/NARC1 cdna-clone 参考资料
                            • Sseidah, N.G. et al., 2003, Proc. Natl. Acad. Sci. USA. 100: 928-933.
                            • Beyer, T.P. et al., 2007, J. Lipid. Res. 48: 1488-1498
                            • Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.
                            • Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
                            • Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.
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