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CD28 / TP44 抗体, 兔多抗

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表达宿主: Human Cells  
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11524-H02H-200
11524-H02H-100
200 µg 
100 µg 
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表达宿主: Human Cells  
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11524-HCCH-200
11524-HCCH-100
200 µg 
100 µg 
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描述: Active  
表达宿主: Human Cells  
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50103-M03H-200
50103-M03H-100
200 µg 
100 µg 
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表达宿主: Human Cells  
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50103-M08H-200
50103-M08H-100
200 µg 
100 µg 
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表达宿主: Human Cells  
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80302-R02H-50
80302-R02H-200
50 µg 
200 µg 
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表达宿主: Human Cells  
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80302-R08H-50
80302-R08H-200
50 µg 
200 µg 
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表达宿主: Human Cells  
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90182-C02H-50
90182-C02H-200
50 µg 
200 µg 
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CD28/TP44 抗体Related Products

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CD28/TP44 antibody 研究背景

CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

小鼠 CD28/TP44 antibody 参考资料
  • Keir ME, et al. (2005) The B7/CD28 costimulatory family in autoimmunity. Immunol Rev. 204: 128-43.
  • Sansom DM, et al. (2006) The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol Rev. 212: 131-48.
  • Bjrgo E, et al. (2010) Novel mechanism of signaling by CD28. Immunol Lett. 129(1): 1-6.
  • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”