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人 Osteomodulin 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
10825-H08H-50
10825-H08H-200
50 µg 
200 µg 
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表达宿主: Human Cells  
  • Slide 1
50451-M08H-50
50451-M08H-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    10825-T16-50
    10825-T16-200
    10825-T16-100
    50 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      10825-RP01-400
      10825-RP01-200
      10825-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      反应性: Mouse  
      应用 : ELISA  
        50451-RP02-50
        50451-RP02-200
        50451-RP02-100
        50 µg 
        200 µg 
        100 µg 
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        反应性: Mouse  
        应用 : 
          50451-R107-50
          50451-R107-100
          50451-R107-1
          50 µg 
          100 µg 
          1 mg 
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          反应性: Mouse  
          应用 : 
            50451-R031-50
            50451-R031-100
            50451-R031-1
            50 µg 
            100 µg 
            1 mg 
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            反应性: Mouse  
            应用 : ELISA  
              50451-RP01-400
              50451-RP01-200
              50451-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart

              Osteomodulin ELISA配对抗体

              检测限: 12.5 pg/ml
              SEK50451-5
              SEK50451-15
              5 Plates 
              15 Plates 
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              Osteomodulin cDNARelated Products

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              Osteomodulin cdna-clone 研究背景

              Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein which belongs to the small leucine-rich proteoglycan (SLRP) family and Class II subfamily. SLRP family proteins are normally found in extracellular matrices, but Osteomodulin is the only member restricted to mineralized tissues. Osteomodulin is primarily expressed by osteoblasts and might have a role in regulation of mineralization. In bone OSAD has been localized in primary spongiosa within the bovine fetal rib growth plate. Moreover, in situ hybridization has shown expression of OSAD in osteoblasts close to the cartilage and bone border in the growth plate of rat femur. OSAD may play an important role during tooth development and biomineralization of dentin. Osteomodulin is a cell binding keratan sulfate proteoglycan which was recently isolated from mineralized bovine bone and subsequently cloned and sequenced. Osteomodulin may be implicated in biomineralization processes. It has a function in binding of osteoblasts via the alpha (V) beta (3)-integrin. It is likely that Osteomodulin is an osteoblast maturation marker that is induced by osteoclast activity. Osteomodulin is also an early marker for terminally differentiated matrix producing osteoblasts.

               Osteomodulin cdna-clone 参考资料
            • Buchaille R, et al. (2000) Expression of the small leucine-rich proteoglycan osteoadherin/osteomodulin in human dental pulp and developing rat teeth. Bone. 27(2): 265-70.
            • Petersson U, et al. (2003) Identification, distribution and expression of osteoadherin during tooth formation. Eur J Oral Sci. 111(2): 128-36.
            • Rehn AP, et al. (2006) Differential regulation of osteoadherin (OSAD) by TGF-beta1 and BMP-2. Biochem Biophys Res Commun. 349(3): 1057-64.
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