Text Size:AAA

大鼠 IGF1/IGF‑I/IGF-1 基因ORF全长cDNA克隆(表达载体)

产品数据评论实验方法
表达宿主: Yeast  
  • Slide 1
10598-HNAY-500
10598-HNAY-100
500 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    10598-R023-50
    10598-R023-100
    50 µg 
    100 µg 
    Add to Cart

    IGF1/IGF‑I/IGF-1 cDNARelated Products

    Related Products

    Featured Reagent Products

    IGF1/IGF‑I/IGF-1 cdna-clone 研究背景

    IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.

    大鼠 IGF1/IGF‑I/IGF-1 cdna-clone 参考资料
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”