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人 FGF21 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
表达宿主: E. coli  
  • Slide 1
10911-H07E-50
10911-H07E-20
50 µg 
20 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
50421-M08H-50
50421-M08H-20
50 µg 
20 µg 
Add to Cart
反应性: Mouse  
应用 : ELISA  
    50421-RP02-50
    50421-RP02-200
    50421-RP02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Mouse  
    应用 : ELISA  
      50421-R005-50
      50421-R005-100
      50 µg 
      100 µg 
      Add to Cart
      反应性: Mouse  
      应用 : ELISA  
        50421-RP01-400
        50421-RP01-200
        50421-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart

        FGF21 cDNARelated Products

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        FGF21 cdna-clone 研究背景

        Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

         FGF21 cdna-clone 参考资料
      • Zhang X, et al. (2008) Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes. 57(5): 1246-53.
      • Lundåsen T, et al. (2007) PPARalpha is a key regulator of hepatic FGF21. Biochem Biophys Res Commun. 360(2): 437-40.
      • Kharitonenkov A, et al. (2005) FGF-21 as a novel metabolic regulator. J Clin Invest. 115(6): 1627-35.
      • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”