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大鼠 Caspase-14/CASP14 基因ORF全长cDNA克隆(表达载体)

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描述: Active  
表达宿主: E. coli  
  • Slide 1
11856-H07E-50
11856-H07E-20
50 µg 
20 µg 
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反应性: Human  
应用 : FCM  
  • Slide 1
11856-MM05-F-25
11856-MM05-F-100
25 Test 
100 Tests 
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反应性: Human  
应用 : ELISA  
    11856-T16-50
    11856-T16-200
    11856-T16-100
    50 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      11856-MM01-50
      11856-MM01-200
      11856-MM01-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        11856-RP01-400
        11856-RP01-200
        11856-RP01-100
        400 µg 
        200 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  IHC-P  
        • Slide 1
        11856-RP02-50
        11856-RP02-200
        11856-RP02-100
        50 µg 
        200 µg 
        100 µg 
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        反应性: Human  
        应用 : IHC-P  IF  ICC/IF  
        • Slide 1
        • Slide 1
        11856-R101-50
        11856-R101-100
        50 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  FCM  
        • Slide 1
        11856-R145-50
        11856-R145-100
        50 µg 
        100 µg 
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        反应性: Human  
        应用 : IHC-P  
        • Slide 1
        11856-R001-50
        11856-R001-100
        50 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  FCM  IF  ICC/IF  
        • Slide 1
        • Slide 1
        11856-MM05-50
        11856-MM05-200
        11856-MM05-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : IHC-P  
        • Slide 1
        11856-MM09-50
        11856-MM09-200
        11856-MM09-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart

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        Caspase-14/CASP14 cdna-clone 研究背景

        Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier.

        大鼠 Caspase-14/CASP14 cdna-clone 参考资料
      • Hu SM, et al. (1998) Caspase-14 is a novel developmentally regulated protease. The journal of biological chemistry. 273: 29648-53.
      • Marc Van De Craen, et al. (1998) Identification of a new caspase homologue: caspase-14. Cell death differ. 5(10): 838-46.
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