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大鼠 Vitronectin/VTN 基因ORF全长cDNA克隆(表达载体)

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
10424-H08H-50
10424-H08H-100
50 µg 
100 µg 
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表达宿主: Human Cells  
  • Slide 1
50585-M08H-500
50585-M08H-50
50585-M08H-100
50585-M08H-1
500 µg 
50 µg 
100 µg 
1 mg 
Add to Cart
反应性: Human  
应用 : 
    10424-MM03-50
    10424-MM03-200
    10424-MM03-100
    10424-MM03-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
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    反应性: Human  
    应用 : ELISA  
      10424-R103-50
      10424-R103-100
      50 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        10424-R102-50
        10424-R102-100
        50 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  WB  
        • Slide 1
        10424-RP01-200
        10424-RP01-100
        200 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  
          10424-MM11-50
          10424-MM11-200
          10424-MM11-100
          10424-MM11-1
          50 µg 
          200 µg 
          100 µg 
          1 mg 
          Add to Cart
          反应性: Mouse  
          应用 : ELISA  
            50585-RP01-400
            50585-RP01-200
            50585-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Mouse  
            应用 : ELISA  IHC-P  
            • Slide 1
            • Slide 1
            50585-RP02-50
            50585-RP02-200
            50585-RP02-100
            50 µg 
            200 µg 
            100 µg 
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            反应性: Mouse  
            应用 : ELISA  IHC-P  
            • Slide 1
            50585-R019-50
            50585-R019-100
            50 µg 
            100 µg 
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            Vitronectin/VTN ELISA配对抗体

            检测限: 62.5 pg/ml
            SEK10424-5
            SEK10424-15
            5 Plates 
            15 Plates 
            Add to Cart

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            Vitronectin/VTN cdna-clone 研究背景

            Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.

            大鼠 Vitronectin/VTN cdna-clone 参考资料
          • Ekmeki OB, et al. (2006) Vitronectin in atherosclerotic disease. Clin Chim Acta. 368(1-2): 77-83.
          • Derer W, et al. (2009) Vitronectin concentrations predict risk in patients undergoing coronary stenting. Circ Cardiovasc Interv. 2(1): 14-9.
          • Heyman L, et al. (2010) Mesothelial vitronectin stimulates migration of ovarian cancer cells. Cell Biol Int. 34(5): 493-502.
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