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人 IL10RB / IL-10RB 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10945-H03H-200
10945-H03H-100
200 µg 
100 µg 
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表达宿主: Human Cells  
  • Slide 1
10945-H08H-20
10945-H08H-100
20 µg 
100 µg 
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表达宿主: Human Cells  
  • Slide 1
50846-M02H-50
50846-M02H-100
50 µg 
100 µg 
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表达宿主: Human Cells  
  • Slide 1
50846-M08H-20
50846-M08H-100
20 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
80184-R02H-50
80184-R02H-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    10945-T16-50
    10945-T16-200
    10945-T16-100
    50 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      10945-RP02-50
      10945-RP02-200
      10945-RP02-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : 
        10945-MM01-50
        10945-MM01-200
        10945-MM01-100
        10945-MM01-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
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        反应性: Human  
        应用 : ELISA  
          10945-RP01-400
          10945-RP01-200
          10945-RP01-100
          400 µg 
          200 µg 
          100 µg 
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          反应性: Human  
          应用 : ELISA  
            10945-MM02-50
            10945-MM02-200
            10945-MM02-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Human  
            应用 : ELISA  WB  
            • Slide 1
            10945-T48-50
            10945-T48-200
            10945-T48-100
            50 µg 
            200 µg 
            100 µg 
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            反应性: Mouse  
            应用 : ELISA  
              50846-RP02-50
              50846-RP02-200
              50846-RP02-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              反应性: Mouse  
              应用 : ELISA  
                50846-RP01-400
                50846-RP01-200
                50846-RP01-100
                400 µg 
                200 µg 
                100 µg 
                Add to Cart

                IL10RB / IL-10RB ELISA配对抗体

                检测限: 78.125 pg/ml
                SEK10945-5
                SEK10945-15
                5 Plates 
                15 Plates 
                Add to Cart

                IL10RB / IL-10RB cDNARelated Products

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                IL10RB / IL-10RB cdna-clone 研究背景

                Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.

                 IL10RB / IL-10RB cdna-clone 参考资料
              • Josephson K, et al. (2001) Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. Immunity. 15 (1): 35-46.
              • Yoo KH, et al. (2011) Association of IL10, IL10RA, and IL10RB polymorphisms with benign prostate hyperplasia in Korean population. J Korean Med Sci. 26(5): 659-64.
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