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人 APLP1 / Amyloid-like 蛋白 1 基因ORF全长cDNA克隆(表达载体), C-Flag 标签

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
13716-H08H-20
13716-H08H-100
20 µg 
100 µg 
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表达宿主: Human Cells  
  • Slide 1
51730-M08H-20
51730-M08H-100
20 µg 
100 µg 
Add to Cart

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APLP1 / Amyloid-like protein 1 cdna-clone 研究背景

APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

 APLP1 / Amyloid-like protein 1 cdna-clone 参考资料
  • Wasco W. et al., 1993, Genomics. 15 (1): 237-9.
  • Needham BE. et al., 2008, J Pathol. 215 (2): 155-63.
  • Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8.
  • Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.
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