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人 SerpinA7 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
10993-H08H-50
10993-H08H-20
50 µg 
20 µg 
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表达宿主: Human Cells  
  • Slide 1
50313-M08H-20
50313-M08H-10
20 µg 
10 µg 
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反应性: Human  
应用 : ELISA  
    10993-R010-50
    10993-R010-100
    50 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      10993-RP02-50
      10993-RP02-200
      10993-RP02-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        10993-RP01-400
        10993-RP01-200
        10993-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          10993-MM02-50
          10993-MM02-200
          10993-MM02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Mouse  
          应用 : ELISA  
            50313-R001-50
            50313-R001-100
            50 µg 
            100 µg 
            Add to Cart
            反应性: Mouse  
            应用 : ELISA  IHC-P  
            • Slide 1
            50313-RP02-50
            50313-RP02-200
            50313-RP02-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Mouse  
            应用 : ELISA  
              50313-RP01-400
              50313-RP01-200
              50313-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart

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              SerpinA7 cdna-clone 研究背景

              Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.

               SerpinA7 cdna-clone 参考资料
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