Anti-FCRL1 Antibody

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Anti-FCRL1 Antibody (Rabbit Polyclonal 抗体) 产品信息

产品名称
Anti-FCRL1 Antibody
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human FCRL1
免疫原
Recombinant Human FCRL1 / FCRH1 protein (Catalog#11536-H08H)
制备方法
Produced in rabbits immunized with purified, recombinant Human FCRL1 / FCRH1 (rh FCRL1 / FCRH1; Catalog#11536-H08H; NP_443170.1; Met 1-Asn 303). FCRL1 / FCRH1 specific IgG was purified by Human FCRL1 / FCRH1 affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-FCRL1 Antibody (Rabbit Polyclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-FCRL1 Antibody: 别称

Anti-CD307a Antibody; Anti-FCRH1 Antibody; Anti-IFGP1 Antibody; Anti-IRTA5 Antibody

FCRL1 背景信息

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains threeIg-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
全称
Fc receptor-like 1
参考文献
  • Du X. et al., 2008, Blood. 111 (1): 338-43.
  • Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9.
  • Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.
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