Kallikrein 11 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All Kallikrein 11 reagents are produced in house and quality controlled, including 6 Kallikrein 11 Antibody, 2 Kallikrein 11 ELISA, 26 Kallikrein 11 Gene, 1 Kallikrein 11 IP Kit, 2 Kallikrein 11 Lysate, 2 Kallikrein 11 Protein, 2 Kallikrein 11 qPCR. All Kallikrein 11 reagents are ready to use.

Kallikrein 11 相关研究领域

Kallikrein 11 分子背景

kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease and PRSS2, is a member of human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which is implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 25 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in brain whereas isoform 2 is preferentially expressed in prostate.

Kallikrein 11 参考文献

  • Yoshida S., et al.,(1998), cDNA cloning and expression of a novel serine protease, TLSP. Biochim. Biophys. Acta 1399:225-228.
  • Mitsui S., et al., (2000), A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate.Biochem. Biophys. Res. Commun. 272:205-211.
  • Yousef G.M., et al.,(2000), Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family.Genomics 63:88-96.