Anti-LAIR2 Antibody (FITC)

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Anti-LAIR2 Antibody (FITC) (Rabbit Monoclonal 抗体) 产品信息

产品名称
Anti-LAIR2 Antibody (FITC)
经验证的应用
FCM
交叉反应
Reacts with: Human
特异性
Human LAIR2
免疫原
Recombinant Human LAIR2 protein (Catalog#10868-H08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human LAIR2 (rh LAIR2; Catalog#10868-H08H; NP_002279.2; Met 1-Pro 152) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
来源
Monoclonal Rabbit IgG Clone #024
纯化
Protein A
缓冲液
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
偶联物
FITC
浓度
10 μl/Test, 0.1 mg/ml
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Anti-LAIR2 Antibody (FITC) (Rabbit Monoclonal 抗体) 图片

Flow cytometric analysis of Human LAIR2(CD306) expression in Jurkat cells. The cells were treated according to manufacturer's manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-LAIR2(CD306) (10868-R024-F). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

Anti-LAIR2 Antibody (FITC): 别称

Anti-CD306 Antibody; Anti-LAIR2 Antibody; Anti-MGC71634 Antibody; Anti-XXbac-BCX535A19.6 Antibody

LAIR2 背景信息

Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.
全称
leukocyte associated immunoglobulin like receptor 2
参考文献
  • Meyaard, L. et al.,1997, Immunity.7:283-290.
  • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
  • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
  • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
  • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
  • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.
  • Immunomodulatory effects of foreskin mesenchymal stromal cells (FSK-MSCs) on natural killer (NK) cells
    Author
    Najar, M;Fayyad-Kazan, M;Meuleman, N;Bron, D;Fayyad-Kazan, H;Lagneaux, L;
    Year
    2017
    Journal
    J. Cell. Physiol.
    Application
    FAC
  • Immunological impact of Wharton's Jelly mesenchymal stromal cells and natural killer cell co-culture
    Author
    Najar, M;Fayyad-Kazan, M;Meuleman, N;Bron, D;Fayyad-Kazan, H;Lagneaux, L;
    Year
    2018
    Journal
    Mol. Cell. Biochem.
    Application
    FAC
  • Mesenchymal stromal cells of the bone marrow and natural killer cells: cell interactions and cross modulation
    Author
    Najar, M;Fayyad-Kazan, M;Meuleman, N;Bron, D;Fayyad-Kazan, H;Lagneaux, L;
    Year
    2018
    Journal
    J Cell Commun Signal
    Application
    FAC
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