CD226 Protein

CD226 Protein Overview

CD226 reagents

CD226 belongs to the immunoglobulin (Ig) superfamily and is expressed on the majority of natural killer (NK) cells, T cells, monocytes, and platelets. Through its interaction with various ligands, including LFA1 (see 153370), CD155 (PVR; 173850), and CD112 (PVRL2; 600798), CD226 plays an important role in T cell- and NK cell-mediated recognition and lysis of tumor cells (summary by Iguchi-Manaka et al., 2008).

CD226 protein name

Recommended name
CD226 antigen
Aliases
DNAM1, DNAM-1, PTA1, TLiSA1
Alternative name
DNAX accessory molecule 1 DNAM-1 CD antigen CD226

CD226 Gene family protein

CD226 Protein Sequence

Species Human CD226 protein
Length 336
Mass (Da) 38614
Sequence Human CD226 protein sequence
Species Mouse CD226 protein
Length 333
Mass (Da) 38063
Sequence Mouse CD226 protein sequence
Species
Length
Mass (Da)
Sequence

CD226 Protein Molecular Weight & PI

CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 19-336 CD226 antigen.

Molecular weight (Da)

36526.46

Theoretical pI

8.23

CD226 Protein Interaction

Recombinant CD226 Protein Feature

CD226 Protein, Human, Recombinant (His Tag)

High Purity
> 97 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
Measured by its binding ability in a functional ELISA . Immobilized human CD226 at 2 μg/ml (100 μl/well) can bind human CD112 with a linear ranger of 6.4-800 ng/ml.

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