Neuropilin-1 cDNA Clone: Expression and Clone Vector / Plasmid
Neuropilin-1 cDNA / Gene Overview
NRP1 gene / cDNA is a protein-coding gene which located on 10p11.22. The NRP1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.230 organisms have orthologs with human gene NRP1.
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Neuropilin-1 cDNA / Gene Sequence
LOCUS NM_001024628 2478 bp mRNA linear PRI 22-JUL-2018
Homo sapiens neuropilin 1 (NRP1), transcript variant 2, mRNA.
This sequence information is just for reference only.