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ABI2 相关研究领域

ABI2 相关信号通路

    ABI2 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    ABI2 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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    ABI2 概述&蛋白信息

    ABI2 研究背景

    亚单位结构: Component of the WAVE1 complex composed of ABI2, CYFIP1 or CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Within the complex, a heterdimer containing NCKAP1 and CYFIP1 interacts with a heterotrimer formed by WAVE1, ABI2 and BRK1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1 (By similarity). Interacts with ABL1 and ABL2. {ECO:0000250, ECO:0000269|PubMed:21107423, ECO:0000269|PubMed:7590236, ECO:0000269|PubMed:8649853}.
    亚细胞定位: Cytoplasm {ECO:0000250}.; Isoform 1: Cell projection, lamellipodium {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Isoform 1 but not isoform 3 is localized to protruding lamellipodia and filopodia tips. {ECO:0000250}.
    翻译后修饰: Is a substrate for ABL1.
    相似的序列: Belongs to the ABI family. {ECO:0000305}.; Contains 1 SH3 domain. {ECO:0000255|PROSITE-ProRule:PRU00192}.; Contains 1 t-SNARE coiled-coil homology domain. {ECO:0000255|PROSITE-ProRule:PRU00202}.
    General information above from UniProt

    ABI2 别称

    ABI-2,ABI2B,AIP-1,AblBP3,argBP1,SSH3BP2,argBPIA,argBPIB, [homo-sapiens]
    AI839867,C130078H13,8430425M24Rik, [mus-musculus]

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