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ANXA5  蛋白,抗体,试剂盒,cDNA克隆

表达宿主: E. coli  
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ANXA5 相关研究领域

ANXA5 相关信号通路

    ANXA5 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    ANXA5 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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    ANXA5 概述&蛋白信息

    ANXA5 研究背景

    基因概述: The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa
    General information above from NCBI
    亚单位结构: Monomer. Binds ATRX and EIF5B (By similarity). Interacts with hepatitis B virus (HBV). {ECO:0000250, ECO:0000269|PubMed:8249278}.
    结构域: A pair of annexin repeats may form one binding site for calcium and phospholipid.
    相关疾病 : DISEASE: Pregnancy loss, recurrent, 3 (RPRGL3) [MIM:614391]: A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions. {ECO:0000269|PubMed:17339269}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
    相似的序列: Belongs to the annexin family. {ECO:0000305}.; Contains 4 annexin repeats. {ECO:0000305}.
    General information above from UniProt

    ANXA5 别称

    PP4,ANX5,ENX2,RPRGL3,HEL-S-7, [homo-sapiens]
    ANX5,ENX2,PP4, [human]
    Anx5,R74653, [mouse]
    Anx5,R74653, [mus-musculus]

    ANXA5 相关文献

  • Cederholm A, et al. (2007) Annexin A5 as a novel player in prevention of atherothrombosis in SLE and in the general population. Ann N Y Acad Sci. 1108: 96-103.
  • Schlaepfer DD, et al. (1992) Inhibition of Protein Kinase C by AnnexinⅤ. Biochemistry. 31: 1886-91.
  • Vermes I, et al. (1995) A novel assay for apoptosis-flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin Ⅴ. J Immunol Methods. 184 (1): 39-51.
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