Integrin alpha V / ITGAV cDNA ORF Clone, Human, C-Myc tag

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Integrin alpha V / ITGAV cDNA ORF Clone, Human, C-Myc tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
3192 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 87 C/T not causing the amino acid variation.
产品特征
Full length Clone DNA of Human integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) with C terminal Myc tag.
质粒
启动子
Enhanced CMV promoter
载体
限制性酶切位点
KpnI + XbaI(6kb+3.19kb)
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Integrin alpha V / ITGAV cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Integrin alpha V / ITGAV cDNA ORF Clone, Human, C-Myc tag: 验证图片

Integrin alpha V / ITGAV cDNA ORF Clone, Human, C-Myc tag: 别称

CD51 cDNA ORF Clone, Human; MSK8 cDNA ORF Clone, Human; VNRA cDNA ORF Clone, Human; VTNR cDNA ORF Clone, Human

Integrin alpha V / ITGAV 背景信息

The members of the integrin alphav (ITGAV) family are widely expressed on many types of tumors and have been reported to be involved into angiogenesis, tumor metastases, and multicellular radioresistance. Recently, it has been shown that the polymorphism of the integrin-alphav subunit encoded by the ITGAV gene plays a role in angiogenesis and is considered as RA susceptibility loci.The integrin alpha(v)beta3, whose alpha(v) subunit is encoded by the ITGAV gene, plays a key role in angiogenesis.
全称
integrin, alpha V
  • Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
    Author
    Kim, H;Wrann, CD;Jedrychowski, M;Vidoni, S;Kitase, Y;Nagano, K;Zhou, C;Chou, J;Parkman, VA;Novick, SJ;Strutzenberg, TS;Pascal, BD;Le, PT;Brooks, DJ;Roche, AM;Gerber, KK;Mattheis, L;Chen, W;Tu, H;Bouxsein, ML;Griffin, PR;Baron, R;Rosen, CJ;Bonewald, LF;Spiegelman, BM;
    Year
    2018
    Journal
    Cell
    Application
    expression
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