Prostate Specific Antigen/KLK3 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All Prostate Specific Antigen/KLK3 reagents are produced in house and quality controlled, including 8 Prostate Specific Antigen/KLK3 Antibody, 2 Prostate Specific Antigen/KLK3 ELISA, 13 Prostate Specific Antigen/KLK3 Gene, 1 Prostate Specific Antigen/KLK3 Lysate, 1 Prostate Specific Antigen/KLK3 Protein, 1 Prostate Specific Antigen/KLK3 qPCR. All Prostate Specific Antigen/KLK3 reagents are ready to use.

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Prostate Specific Antigen/KLK3 分子背景

KLK3(Kallikrein 3), also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.KLK3 contains one peptidase S1 domain.KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Prostate Specific Antigen/KLK3 参考文献

  • Koistinen H, et al. (2008) Development of peptides specifically modulating the activity of KLK2 and KLK3. Biol Chem. 389(6): 633-42.
  • Yousef GM, et al. (2002) Kallikreins, steroid hormones and ovarian cancer: is there a link? Minerva Endocrinol. 27(3): 157-66.
  • Parikh H, et al. (2011) Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels. Hum Genet. 129(6): 675-85.