LCAT (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All LCAT reagents are produced in house and quality controlled, including 1 LCAT Antibody, 28 LCAT Gene, 1 LCAT Lysate, 1 LCAT Protein, 1 LCAT qPCR. All LCAT reagents are ready to use.

LCAT 相关研究领域

LCAT 分子背景

Lecithin:cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma,thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport.Lecithin cholesterol acyltransferase (LCAT) plays a pivotal role in HDL metabolism.LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. LCAT may also modify oxidative and inflammatory processes, as supported by an inverse relationship with HDL antioxidative functionality and a positive relationship with high-sensitivity C-reactive protein (hsCRP).