Anti-Periostin Antibody

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Anti-Periostin Antibody (Rabbit Monoclonal 抗体) 产品信息

产品名称
Anti-Periostin Antibody
经验证的应用
ELISA
交叉反应
Reacts with: Mouse
特异性
Mouse Periostin
No cross-reactivity in ELISA with
Human POSTN
免疫原
Recombinant Mouse Periostin / POSTN Protein (Catalog#50450-M08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Periostin / POSTN (rM Periostin / POSTN; Catalog#50450-M08H; Met 1-Gln 811; NP_056599.1) .
来源
Monoclonal Rabbit IgG Clone #031
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Periostin Antibody (Rabbit Monoclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Periostin Antibody: 别称

Anti-A630052E07Rik Antibody; Anti-AI747096 Antibody; Anti-OSF-2 Antibody; Anti-Osf2 Antibody; Anti-peri Antibody; Anti-PLF Antibody; Anti-PN Antibody

Periostin 背景信息

Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.
全称
periostin, osteoblast specific factor
参考文献
  • Kudo,Y. et al., 2007, Histol Histopathol. 22 (10):1167-1174.
  • Li, J.S. et al., 2007, World J Gastroenterol. 13 (39): 5261-5266.
  • Oku, E. et al., 2008, Int J Hematol. 88 (1): 57-63.
  • Hamilton, D.W. et al., 2008, J Cell Commun Signal. 2(1-2):9-17.
  • Puglisi, F.J et al., 2008, Clin Pathol. 61 (4): 494-498.
  • Conway, S. J. et al., 2008, Curr Genomics. 9 (8): 548-555.
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