FLT4 Matched ELISA Antibody Pair Set,Human

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FLT4 Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
FLT4 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human FLT4
线性范围
78.13-5000 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of mouse anti-VEGFR3 monoclonal antibody. Dilute to a working concentration of 2 μg/mL in CBS before coating (Catalog: # 10806-MM02)
2. Detection Antibody 0.4 mg/mL mouse anti-VEGFR3 monoclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to working concentration of 1 μg/mL in detection antibody dilution buffer before use (Catalog: # 10806-MM06)
3. Standard Each vial contains 80 ng of recombinant VEGFR3. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A six-point standard curve usi ng 2-fold serial dilutions in sample dilution buffer, and a high standard of 5 ng/mL is recommended
产品概述
This FLT4 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human FLT4 . It contains Human FLT4 capture antibody, Human FLT4 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human FLT4 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

FLT4 Matched ELISA Antibody Pair Set,Human 图片

FLT4 Matched ELISA Antibody Pair Set,Human: 别称

FLT-4 Matched ELISA Antibody Pair Set, Human; FLT-41 Matched ELISA Antibody Pair Set, Human; FLT41 Matched ELISA Antibody Pair Set, Human; LMPH1A Matched ELISA Antibody Pair Set, Human; PCL Matched ELISA Antibody Pair Set, Human; VEGF Receptor 3 Matched ELISA Antibody Pair Set, Human; VEGFR-3 Matched ELISA Antibody Pair Set, Human; VEGFR3 Matched ELISA Antibody Pair Set, Human

FLT4 背景信息

Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.
全称
fms related tyrosine kinase 4
参考文献
  • Shushanov S, et al. (2000)VEGFc and VEGFR3 expression in human thyroid pathologies. Int J Cancer.86(1): 47-52.
  • Iljin K, et al. (2001) VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J. 15(6): 1028-36.
  • Liu XE, et al. (2004) Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 10(3): 352-5.
  • Stearns ME, et al. (2004) Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Lab Invest. 84(6): 785-95.
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