Anti-Thrombopoietin Antibody

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Anti-Thrombopoietin Antibody (Rabbit Polyclonal 抗体) 产品信息

产品名称
Anti-Thrombopoietin Antibody
经验证的应用
WB
交叉反应
Reacts with: Mouse
特异性
Mouse Thrombopoietin
免疫原
Recombinant Mouse Thrombopoietin/THPO Protein (Catalog#50146-M08H)
制备方法
Produced in rabbits immunized with purified, recombinant Mouse Thrombopoietin/THPO (rM Thrombopoietin/THPO; Catalog#50146-M08H; NP_033405.1; Met1-Thr356). Thrombopoietin/THPO specific IgG was purified by Mouse Thrombopoietin/THPO affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
PBS, pH7.0 with 0.03% Proclin300
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-Thrombopoietin Antibody (Rabbit Polyclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
WB 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Thrombopoietin Antibody (Rabbit Polyclonal 抗体) 图片

Anti-THPO rabbit polyclonal antibody at 1:500 dilution

Lane A: Mouse liver tissue lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size:38 kDa

Anti-Thrombopoietin Antibody: 别称

Anti-Mgdf Antibody; Anti-Ml Antibody; Anti-Mpllg Antibody; Anti-Tpo Antibody

Thrombopoietin 背景信息

Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.
全称
thrombopoietin
参考文献
  • Ryu T,et al.(2003) Thrombopoietin-producing hepatocellular carcinoma. Intern Med. 42(8): 730-4.
  • Higashihara M,et al. (2003) Thrombopoietin-producing tumor. Intern Med. 42(8): 632-3?
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