Anti-ACOT13/THEM2 Antibody, Rabbit Polyclonal

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Anti-ACOT13/THEM2 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-ACOT13/THEM2 Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human ACOT13/THEM2
免疫原
Recombinant Human ACOT13 protein (Catalog#15437-H07E)
制备方法
Produced in rabbits immunized with purified, recombinant Human ACOT13 (rh ACOT13; Catalog#15437-H07E; NP_060943.1; Met1-Asn140). Total IgG was purified by Protein A affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-ACOT13/THEM2 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-ACOT13/THEM2 Antibody, Rabbit Polyclonal: 别称

Anti-ACOT13 Antibody; Anti-HT012 Antibody; Anti-PNAS-27 Antibody; Anti-THEM2 Antibody

ACOT13/THEM2 背景信息

The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their biological functions remain incompletely understood. Thioesterase superfamily member 2 (Them2; synonym Acot13) is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. Using Them2(-/-) mice, we have demonstrated key roles for Them2 in regulating hepatic glucose and lipid metabolism. Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-CoAs, but their biological functions remain unknown. Thioesterase superfamily member 2 (Them2; synonym Acot13) is a broadly expressed mitochondria-associated Acot. Them2 was previously identified as an interacting protein of phosphatidylcholine transfer protein (PC-TP).
全称
acyl-CoA thioesterase 13
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