Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal

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Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human Adenylate Kinase 1
免疫原
Recombinant Human AK1 / Adenylate kinase 1 protein (Catalog#12442-H07E)
制备方法
Produced in rabbits immunized with purified, recombinant Human AK1 / Adenylate kinase 1 (rh AK1; Catalog#12442-H07E; AAH01116.1; Met1-Lys194). Total IgG was purified by Protein A affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal: 别称

Anti-HTL-S-58j Antibody

Adenylate Kinase 1 背景信息

The adenylate kinase (AK) isoforms network plays an important role in the intracellular energy transfer processes, the maintenance of energy homeostasis, and it is a major player in AMP metabolic signaling circuits in some highly-differentiated cells. Three other biomarkers (AK1, CLIC1, and SOD1) were significantly increased in both adenoma and early colorectal cancer patient plasma samples and in plasma from colorectal cancer mouse models at preclinical stages compared with controls.Which can contribute to the detection of early-stage colorectal cancer and adenomas.
全称
adenylate kinase 1
参考文献
  • Lu Q, et al. (1996) Adenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolism. Proc Natl Acad Sci. 93 (12): 5720-5.
  • Dzeja P, et al. (2009) Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing. Int J Mol Sci. 10 (4): 1729-72.
  • Lagresle-Peyrou C, et al. (2008) Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nature Genetics. 41: 106 - 11.
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