Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal

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Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human Aquaporin 9/AQP9
免疫原
A synthetic peptide corresponding to the C-terminus of the Human Aquaporin 9/AQP9
制备方法
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human Aquaporin 9/AQP9, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:200-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human Aquaporin 9 in human liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.

Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal: 别称

Anti-AQP-9 Antibody; Anti-HsT17287 Antibody; Anti-SSC1 Antibody

Aquaporin 9/AQP9 背景信息

Aquaporins (AQPs) are a family of small integral membrane proteins made up of 6 hydrophobic, a-helical, membrane-spanning domains surrounding a highly selective aqueous pore. AQP3, AQP7, and AQP9, termed aqua-glyceroporins, are known to be involved in the transport of water, glycerol, and other small molecules. AQP3 and AQP9 facilitate both transcellular osmotic water flow and glycerol transport as pore-like passive transporters in the keratinocytes of oral epithelia, and may play a key role in not only hydration and the permeability barrier, but also cell proliferation, differentiation, migration, development, and wound healing by generating ATP. Aquaporin-9 (AQP9) is a membrane protein channel that is permeable to a range of small solutes, including glycerol, urea and nucleobases. Aquaporin-9 (AQP9) expression is associated with arsenic sensitivity in leukemia cells. AQP9 might be a novel predictor for the benefit of 5-FU-based chemotherapy in CRC. The identification of AQP9-induced tumor sensitivity to 5-FU highlights the role of AQP9 in regulating chemosensitivity in CRC. aquaporin 9 (AQP9) in the prostate was strictly upregulated by androgen and may represent a novel therapeutic target for several cancers. AQP9 molecular expression mediated by insulin in a concentration-dependent manner in human placenta and provide new evidence that in preeclamptic placentas the mechanisms of insulin signaling may be altered, producing an overexpression of AQP9 that does not correlate with an increase in its functionality.
全称
aquaporin 9
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