Anti-ATF1 Antibody, Rabbit Polyclonal

1/2
Price:
Size:
Number:

Anti-ATF1 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-ATF1 Antibody, Rabbit Polyclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human ATF1
免疫原
A synthetic peptide corresponding to the N-terminus of the Human ATF1 / Protein TREB36
制备方法
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human ATF1 / Protein TREB36, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-ATF1 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-ATF1 Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human ATF1 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunochemical staining of human ATF1 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-ATF1 Antibody, Rabbit Polyclonal: 别称

Anti-EWS-ATF1 Antibody; Anti-FUS/ATF-1 Antibody; Anti-TREB36 Antibody

ATF1 背景信息

Activating transcription factor 1 (ATF1) and RAS genes were significantly up-regulated in tumours of both primary and recurrent cervical cancer mouse model, and they can also be detected in the blood exosomes of the mouse model. Our results indicated that ATF1 and RAS could be potential candidate biomarkers for cervical cancer in early diagnosis. ATF1 and RAS genes were found significantly elevated in tumours of primary and recurrent cervical cancer mouse model, and they were also detected in the blood exosomes. Therefore, ATF1 and RAS could be used as a diagnostic marker for cervical cancer in the future. The transcription factor Atf1 is known to promote cell survival during various stress conditions in Schizosaccharomyces pombe by activating the expression of appropriate genes. It can also activate transcription of other important genes responsible for cell cycle progression. An Atf1-dependent increase in the expression of cell division promoting genes will oppose activation of checkpoints necessary to ensure repairs and cell survival during stress.
全称
activating transcription factor 1
Related Pathways
  • MAPK-Erk Pathway
    MAPK-Erk Pathway
  • P38 MAPK Signaling Pathway
    P38 MAPK Signaling Pathway
  • IL1 signaling pathway
    IL1 signaling pathway
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.