Recombinant Human BCL2L11 / Bim Protein (Catalog#13816-H07E)
Produced in rabbits immunized with purified, recombinant Human BCL2L11 / Bim (rh BCL2L11 / Bim; Catalog#13816-H07E; NP_006529.1; Ala2-Arg120). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-Bim Antibody, Rabbit Polyclonal 经验证的应用
Please Note: Optimal concentrations/dilutions should be determined by the end user.
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L11 contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. BCL2L11 gene functions as an essential initiator of apoptosis in thymocyte-negative selection.
BCL2-like 11 (apoptosis facilitator)
AKT Signaling Pathway
Day Catherine L. et al., 2004, Biochem J. 377 (3): 597-605.
Murray S. et al., 2001, Cytogenet Cell Genet. 92 (3-4): 353.
Hsu SY. et al., 1998,Mol Endocrinol. 12 (9): 1432-40.