Anti-Cbl-c Antibody, Rabbit Polyclonal

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Anti-Cbl-c Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-Cbl-c Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human Cbl-c
免疫原
Recombinant Human Cbl-c / CBL-3 protein (Catalog#15659-H20B)
制备方法
Produced in rabbits immunized with purified, recombinant Human Cbl-c / CBL-3 (rh Cbl-c / CBL-3; Catalog#15659-H20B; AAH28915.1; Met1-Ala474). Cbl-c / CBL-3 specific IgG was purified by Human Cbl-c / CBL-3 affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cbl-c Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cbl-c Antibody, Rabbit Polyclonal: 别称

Anti-CBL-3 Antibody; Anti-CBL-SL Antibody; Anti-RNF57 Antibody

Cbl-c 背景信息

CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.
全称
Cbl proto-oncogene C, E3 ubiquitin protein ligase
参考文献
  • Kim M. et al., 1999, Gene. 239 (1): 145-54.
  • Courbard JR. et al., 2003, J. Biol. Chem. 277 (47): 45267-75.
  • Keane MM. et al., 1999, Oncogene. 18 (22): 3365-75.
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