Recombinant Anti-CD160 Antibody (APC), Rabbit Monoclonal

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Recombinant Anti-CD160 Antibody (APC), Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CD160 Antibody (APC), Rabbit Monoclonal
经验证的应用
FCM
交叉反应
Reacts with: Human
特异性
Human CD160
免疫原
Recombinant Human CD160 Protein (Catalog#12191-H08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD160 (rh CD160; Catalog#12191-H08H; NP_008984.1; Met1-Leu158) and conjugated with APC under optimum conditions, the unreacted APC was removed.
来源
Monoclonal Rabbit IgG Clone #275
纯化
Protein A
缓冲液
Aqueous solution containing 0.5% BSA and 0.1% sodium azide
偶联物
APC
浓度
10 μl/Test, 0.1 mg/ml
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Recombinant Anti-CD160 Antibody (APC), Rabbit Monoclonal 图片

Flow cytometric analysis of Human CD160 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD160. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.

Recombinant Anti-CD160 Antibody (APC), Rabbit Monoclonal: 别称

Anti-BY55 Antibody; Anti-NK1 Antibody; Anti-NK28 Antibody

CD160 背景信息

CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
全称
CD160 molecule
研究领域
参考文献
  • Barakonyi A. et al., 2004, J Immunol.173 (9): 5349-54.
  • Rabot M. et al., 2006, Transpl Immunol. 17 (1): 36-8.
  • Abecassis S. et al., 2007, J Invest Dermatol. 127?(5): 1161-6.
  • Giustiniani J.?et al., 2007, J Immunol. 178 (3): 1293-300.
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