Recombinant Anti-CD38 Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CD38 Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CD38 Antibody, Rabbit Monoclonal
经验证的应用
WB,ELISA,IP
交叉反应
Reacts with: Human
特异性
Human CD38
免疫原
Recombinant Human CD38 protein (Catalog#10818-H08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD38 (rh CD38; Catalog#10818-H08H; NP_001766.2; Val 43-Ile 300).
来源
Monoclonal Rabbit IgG Clone #003
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-CD38 Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
WB 1:2000-1:10000
ELISA 1:5000-1:10000
IP IP:1-5 μL/mg of lysate
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-CD38 Antibody, Rabbit Monoclonal 图片

Anti-CD38 rabbit monoclonal antibody at 1:1000 dilution

Lane A: Jurkat Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:34 kDa

Observed band size:50 kDa

CD38 was immunoprecipitated using:

Lane A:0.5 mg Jurkat Whole Cell Lysate

4µL anti-CD38 rabbit monoclonal antibody and 60 μg of Immunomagnetic beads Protein A/G.

Primary antibody:

Anti-CD38 rabbit monoclonal antibody,at 1:100 dilution

Secondary antibody:

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size: 45 kDa

Observed band size :45 kDa

Recombinant Anti-CD38 Antibody, Rabbit Monoclonal: 别称

Anti-ADPRC 1 Antibody; Anti-ADPRC1 Antibody; Anti-T10 Antibody

CD38 背景信息

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.
全称
CD38 molecule
研究领域
参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
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