Anti-CD48 Antibody, Mouse Monoclonal

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Anti-CD48 Antibody, Mouse Monoclonal 产品信息

产品名称
Anti-CD48 Antibody, Mouse Monoclonal
经验证的应用
ELISA(Cap)
交叉反应
Reacts with: Human
特异性
Human CD48
免疫原
Recombinant Human CD48 protein (Catalog#10797-H08H)
制备方法
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD48 (rhCD48; Catalog#10797-H08H; NP_001769.2; Met 1-Ser 220). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
来源
Monoclonal Mouse IgG1 Clone #9B1A3F6
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CD48 Antibody, Mouse Monoclonal 经验证的应用

Notes
ELISA(Cap): This antibody will detect Human CD48 / Blast-1 in ELISA pair set (Catalog: # SEKA10797). In a sandwich ELISA, it can be used as capture antibody when paired with (Catalog: # 10797-R007).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CD48 Antibody, Mouse Monoclonal: 别称

Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-Blast-1 Antibody; Anti-BLAST1 Antibody; Anti-hCD48 Antibody; Anti-mCD48 Antibody; Anti-MEM-102 Antibody; Anti-SLAMF2 Antibody

CD48 背景信息

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
全称
CD48 molecule
研究领域
参考文献
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
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