Recombinant Anti-CLEC4D Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CLEC4D Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CLEC4D Antibody, Rabbit Monoclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human CLEC4D
免疫原
Recombinant Human CLEC4D Protein (Catalog#H07H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CLEC4D (rh CLEC4D; Catalog#H07H; Gly 52-Asn 215; NP_525126.2).
来源
Monoclonal Rabbit IgG Clone #001
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-CLEC4D Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-CLEC4D Antibody, Rabbit Monoclonal: 别称

Anti-CD368 Antibody; Anti-CLEC-6 Antibody; Anti-CLEC6 Antibody; Anti-CLECSF8 Antibody; Anti-Dectin-3 Antibody; Anti-MCL Antibody; Anti-MPCL Antibody

CLEC4D 背景信息

C-type lectin (CLEC) family is a type of carbohydrate-binding protein domain named lectin. C-type lectins are the most diverse and prevalent lectin family in immunity with its requirement for calcium for binding. Proteins including a C-type lectin domain have diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. There are at least 14 types of C-type lectins: typeⅠto typeⅩⅣ. CLEC4D(CLECSF8) is a typeⅡ membrane glycoprotein belonging to the C-type lectin family, with restricted expression in the monocyte/macrophage lineage. It plays important roles in the function of macrophages.
全称
C-type lectin domain family 4, member D
参考文献
  • Johnson KD, et al. (2007) Friend of GATA-1-independent Transcriptional Repression: A Novel Mode of GATA-1 Function. Blood. 109 (12): 5230-3.
  • Arce I, et al. (2004) The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur J Immunol. 34 (1): 210-20.
  • Marshall AS, et al. (2006) Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation. Eur J Immunol. 36 (8): 2159-69.
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