Recombinant Anti-CRELD1 Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CRELD1 Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CRELD1 Antibody, Rabbit Monoclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human CRELD1
免疫原
Recombinant Human CRELD1 protein (Catalog#13411-H08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CRELD1 (rh CRELD1; Catalog#13411-H08H; NP_001070883.1; Met1-Glu362).
来源
Monoclonal Rabbit IgG Clone #116
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-CRELD1 Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-CRELD1 Antibody, Rabbit Monoclonal: 别称

Anti-AVSD2 Antibody; Anti-CIRRIN Antibody

CRELD1 背景信息

CRELD1 is a transmembrane glycoprotein. Epidermal growth factor(EGF)­like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.
全称
cysteine-rich with EGF-like domains 1
参考文献
  • Robinson SW, et al. (2003) Missense Mutations in CRELD1 Are Associated with Cardiac Atrioventricular Septal Defects. Am J Hum Genet. 72(4):1047-52.
  • Zatyka M, et al. (2005) Analysis of CRELD1 as a candidate 3p25 atrioventicular septal defect locus (AVSD2). Clin Genet. 67(6):526-8.
  • Stelzl U, et al. (2005) A human protein-protein interaction network: a resource for annotating the proteome. Cell. 122(6):957-68.
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