Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal

1/3
Price:
Size:
Number:

Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal
经验证的应用
WB,IHC-P
交叉反应
Reacts with: Human
特异性
Human Cytokeratin 19/KRT19
免疫原
A synthetic peptide corresponding to the N-terminus of the human KRT19
制备方法
Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human KRT19 , and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
WB 1:500-1:1000
IHC-P 1:5000-1:25000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human KRT19 in human thyroid cancer with rabbit polyclonal antibody at 1:15000 dilution, formalin-fixed paraffin embedded sections.
Immunochemical staining of human KRT19 in human hepatoma with rabbit polyclonal antibody at 1:15000 dilution, formalin-fixed paraffin embedded sections.

Anti-KRT19 rabbit polyclonal antibody at 1:500 dilution

Lane A: HepG2 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:40 kDa

Observed band size:40 kDa

Anti-Cytokeratin 19/KRT19 Antibody, Rabbit Polyclonal: 别称

Anti-CK19 Antibody; Anti-K19 Antibody; Anti-K1CS Antibody

Cytokeratin 19/KRT19 背景信息

Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein, which is responsible for structural rigidity and multipurpose scaffolds. In several cancers, KRT19 is overexpressed and may play a crucial role in tumorigenic transformation. The KRT19 gene encodes cytokeratin 19, an element of the cytoskeleton whose expression is frequently altered in renal cell carcinoma (RCC).KRT19 was identified as one of the key biomarkers for distinguishing cholangiocarcinoma (CCA) and hepatocellular carcinoma. Expression of KRT19 was specifically high in breast cancers and significantly correlated with their invasiveness. Moreover, knockdown of KRT19 led to increased proliferation, migration, invasion, drug resistance, and sphere formation in breast cancer cells via an upregulated NOTCH signaling pathway.
全称
keratin 19, type I
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.