Anti-Cytokeratin 5/KRT5 Antibody

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Anti-Cytokeratin 5/KRT5 Antibody (Rabbit Polyclonal 抗体) 产品信息

产品名称
Anti-Cytokeratin 5/KRT5 Antibody
经验证的应用
WB
交叉反应
Reacts with: Human
特异性
Human Cytokeratin 5/KRT5
免疫原
A synthetic peptide corresponding to the center region of the human KRT5
制备方法
Produced in rabbits immunized with A synthetic peptide corresponding to the center region of the human KRT5 , and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cytokeratin 5/KRT5 Antibody (Rabbit Polyclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
WB 1:1000-1:5000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cytokeratin 5/KRT5 Antibody (Rabbit Polyclonal 抗体) 图片

Anti-KRT5 rabbit polyclonal antibody at 1:1000 dilution

Lane A: HCT116 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:62 kDa

Observed band size:55 kDa

Anti-Cytokeratin 5/KRT5 Antibody: 别称

Anti-CK5 Antibody; Anti-DDD Antibody; Anti-DDD1 Antibody; Anti-EBS2 Antibody; Anti-K5 Antibody; Anti-KRT5A Antibody

Cytokeratin 5/KRT5 背景信息

Keratin 5 is the major type II keratin of the basal cells of epidermis and of other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
全称
keratin 5, type II
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