Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal

RRID Number: AB_2860127
EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human Galectin 3/LGALS3
No cross-reactivity in ELISA with
Human Galectin-1 / LGALS1
Human Galectin-7 / LGALS7
Human Galectin-8 / LGALS8
免疫原
Recombinant Human Galectin-3 / LGALS3 protein (Catalog#10289-HNAE)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human Galectin-3 / LGALS3 (rh Galectin-3 / LGALS3; Catalog#10289-HNAE; P17931; Met1-Ile250).
来源
Monoclonal Rabbit IgG Clone #102
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal 图片

Immunochemical staining of human Galectin3 in human lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human Galectin3 in human colon carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal: 别称

Anti-CBP35 Antibody; Anti-GAL3 Antibody; Anti-GALBP Antibody; Anti-GALIG Antibody; Anti-L31 Antibody; Anti-LGALS2 Antibody; Anti-MAC2 Antibody

Galectin 3/LGALS3 背景信息

LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
全称
lectin, galactoside-binding, soluble, 3
参考文献
  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.
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