Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal

1/2
Price:
Size:
Number:

Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal 产品信息

产品名称
Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human GOLPH2/GOLM1
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
免疫原
Recombinant Human GOLM1 / GP73 protein (Catalog#13066-H08H)
制备方法
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GOLM1 / GP73 (rh GOLM1 / GP73; Catalog#13066-H08H; Q8NBJ4-1; Val 40-Leu 401). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
来源
Monoclonal Mouse IgG1 Clone #9C2D3
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:50-1:200
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal 图片

Immunochemical staining of human GOLM1 in human liver with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of hepatocyte and interlobular bile duct.
Immunochemical staining of human GOLM1 in human endometrium with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of uterine gland.

Anti-GOLPH2/GOLM1 Antibody, Mouse Monoclonal: 别称

Anti-bA379P1.3 Antibody; Anti-C9orf155 Antibody; Anti-GOLPH2 Antibody; Anti-GP73 Antibody; Anti-HEL46 Antibody; Anti-PSEC0257 Antibody

GOLPH2/GOLM1 背景信息

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.
全称
golgi membrane protein 1
参考文献
  • Kladney R.D., et al.,(2000), GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 249:53-65.
  • Clark H.F., et al., (2003), The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Genome Res. 13:2265-2270.
  • Puri S., et al.,(2002), Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption.Traffic 3:641-653.
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.