Anti-LIN28A Antibody, Rabbit Polyclonal

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Anti-LIN28A Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-LIN28A Antibody, Rabbit Polyclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human LIN28A
免疫原
A synthetic peptide corresponding to the center region of the human Lin28A
制备方法
Produced in rabbits immunized with A synthetic peptide corresponding to the center region of the human Lin28A , and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-LIN28A Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-LIN28A Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human LIN28A in human testis with rabbit polyclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human LIN28A in human glioma with rabbit polyclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Anti-LIN28A Antibody, Rabbit Polyclonal: 别称

Anti-CSDD1 Antibody; Anti-LIN-28 Antibody; Anti-lin-28A Antibody; Anti-LIN28 Antibody; Anti-ZCCHC1 Antibody

LIN28A 背景信息

LIN28A (Lin-28 Homolog A) is a Protein Coding gene. LIN28A, a highly-conserved RNA binding protein expressed during embryogenesis, plays roles in development, pluripotency, metabolism, as well as tissue repair in adults. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. LIN28 plays a critical role in the developmental transition, glucose metabolism, and tumorigenesis. At the molecular level, LIN28 is known to repress the maturation of let-7 microRNAs and enhance the translation of certain mRNAs. Aberrant expression of this gene is associated with cancer progression in multiple tissues. LIN28A is an important factor in tumor cells and ESCs, it is an inhibitor of the intracellular endoplasmic reticulum (ER)related protein translation in ESCs.
全称
lin-28 homolog A (C. elegans)
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