Recombinant Anti-MIP-5 Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-MIP-5 Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-MIP-5 Antibody, Rabbit Monoclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human MIP-5
免疫原
Recombinant Human CCL15 / MIP-5 / MIP-1 delta protein (Catalog#10898-H08E)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CCL15 / MIP-5 / MIP-1 delta (rh CCL15 / MIP-5 / MIP-1 delta; Catalog#10898-H08E; Q16663-1; Gln22-Ile113).
来源
Monoclonal Rabbit IgG Clone #001
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-MIP-5 Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-MIP-5 Antibody, Rabbit Monoclonal: 别称

Anti-HCC-2 Antibody; Anti-HMRP-2B Antibody; Anti-LKN-1 Antibody; Anti-LKN1 Antibody; Anti-MIP-1 delta Antibody; Anti-MIP-1D Antibody; Anti-MIP-5 Antibody; Anti-MRP-2B Antibody; Anti-NCC-3 Antibody; Anti-NCC3 Antibody; Anti-SCYA15 Antibody; Anti-SCYL3 Antibody; Anti-SY15 Antibody

MIP-5 背景信息

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
全称
chemokine (C-C motif) ligand 15
参考文献
  • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
  • Youn, et al. (1997) Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3. J Immun. 159: 5201-5.
  • Coulin, et al. (1997) Characterization of macrophage inflammatory protein-5 / human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines. Europ J Biochem. 248: 507-15.
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