Anti-MYH11 Antibody, Rabbit Polyclonal

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Anti-MYH11 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-MYH11 Antibody, Rabbit Polyclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human MYH11
免疫原
A synthetic peptide corresponding to the C-terminus of the human MYH11
制备方法
Produced in rabbits immunized with A synthetic peptide corresponding to the C-terminus of the human MYH11, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-MYH11 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:1000-1:4000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-MYH11 Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human MYH11 in human uterus with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Immunochemical staining of human MYH11 in human prostate with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Anti-MYH11 Antibody, Rabbit Polyclonal: 别称

Anti-AAT4 Antibody; Anti-FAA4 Antibody; Anti-SMHC Antibody; Anti-SMMHC Antibody

MYH11 背景信息

The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. MYH11 functions as a contractile protein, converting chemical energy into mechanical energy through adenosine triphosphate hydrolysis.MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. Mutations in myosin heavy chain (MYH11) cause autosomal dominant inheritance of thoracic aortic aneurysms and dissections. At the same time, rare, nonsynonymous variants in MYH11 that are predicted to disrupt protein function but do not cause inherited aortic disease are common in the general population. The human smooth muscle myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe.
全称
myosin, heavy polypeptide 11, smooth muscle
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