Anti-NEUROD1 Antibody, Rabbit Polyclonal

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Anti-NEUROD1 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-NEUROD1 Antibody, Rabbit Polyclonal
经验证的应用
IHC-P
交叉反应
Reacts with: Human
特异性
Human NEUROD1
免疫原
A synthetic peptide corresponding to the N-terminus of the human NeuroD1
制备方法
Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human NeuroD1, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-NEUROD1 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:1000-1:4000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-NEUROD1 Antibody, Rabbit Polyclonal 图片

Immunochemical staining of human NEUROD1 in human hepatoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Immunochemical staining of human NEUROD1 in human endometrium with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Anti-NEUROD1 Antibody, Rabbit Polyclonal: 别称

Anti-BETA2 Antibody; Anti-BHF-1 Antibody; Anti-bHLHa3 Antibody; Anti-MODY6 Antibody; Anti-NEUROD Antibody

NEUROD1 背景信息

NEUROD1 (Neuronal Differentiation 1, also known as BETA2) is a Protein Coding gene. NEUROD1 encodes a transcription factor expressed in the endocrine pancreas and involved in beta-cell development, function, and mechanisms of apoptosis. The protein is a tissue-specific basic helix loop helix (bHLH) protein involved in the development and maintenance of the endocrine pancreas and neuronal elements. It forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. NEUROD1 is expressed in both developing and mature beta-cells. Loss of NEUROD1 causes ataxia, cerebellar hypoplasia, sensorineural deafness, and severe retinal dystrophy in mice. Diseases associated with NEUROD1 include Maturity-Onset Diabetes Of The Young, Type 6 and Diabetes Mellitus, Noninsulin-Dependent.
全称
neurogenic differentiation 1
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