Anti-PIM1 Antibody, Rabbit Polyclonal

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Anti-PIM1 Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-PIM1 Antibody, Rabbit Polyclonal
经验证的应用
WB
交叉反应
Reacts with: Human
Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
特异性
Human PIM1
免疫原
A synthetic peptide corresponding to the N-terminus of the human PIM1
制备方法
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the human PIM1, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-PIM1 Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
WB 1:500-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-PIM1 Antibody, Rabbit Polyclonal 图片

Anti-PIM1 rabbit polyclonal antibody at 1:500 dilution

Lane A: Jurkat Whole Cell Lysate

Lane B: U937 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:45 kDa

Observed band size:32 kDa

Anti-PIM1 Antibody, Rabbit Polyclonal: 别称

Anti-PIM Antibody

PIM1 背景信息

PIM1 protease in mitochondria belongs to a conserved family of ATP-dependent proteases, which includes the Escherichia coli Lon protease. Yeast cells lacking PIM1 are largely defective in degrading misfolded proteins in the mitochondrial matrix, are respiratory deficient, and lose integrity of mitochondrial DNA. PIM1 could be a new potential therapeutic target in the prevention and treatment of human-specific autoimmune diseases because of its ability to modulate the immunosuppressive activity of human Tregs.
全称
Pim-1 proto-oncogene, serine/threonine kinase
研究领域
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