Anti-RHCE Antibody, Rabbit Polyclonal

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Anti-RHCE Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-RHCE Antibody, Rabbit Polyclonal
经验证的应用
WB
交叉反应
Reacts with: Human
特异性
Human RHCE
免疫原
A synthetic peptide corresponding to the center region of the Human RHCE/CD240CE
制备方法
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human RHCE/CD240CE, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-RHCE Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
WB 1:500-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-RHCE Antibody, Rabbit Polyclonal 图片

Anti-CD240CE rabbit polyclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lane B: A431 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:46 kDa

Observed band size:54 kDa

Anti-RHCE Antibody, Rabbit Polyclonal: 别称

Anti-CD240CE Antibody; Anti-RH Antibody; Anti-RH30A Antibody; Anti-Rh4 Antibody; Anti-RHC Antibody; Anti-RHE Antibody; Anti-RhIVb(J) Antibody; Anti-RHIXB Antibody; Anti-RHPI Antibody; Anti-RhVI Antibody; Anti-RhVIII Antibody

RHCE 背景信息

RHCE (Rh Blood Group CcEe Antigens) is a Protein Coding gene. The RHCE gene, located on 1p36.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. The RH blood group system has many RHCE variant alleles that have arisen through gene conversion or nucleotide changes. A mutation in gene RHCE results in amorph-type Rh-null disease. RHCE may be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. Diseases associated with RHCE include Rh-Null, Amorph Type, and Retinohepatoendocrinologic Syndrome. 95 organisms have orthologs with the human gene RHCE.
全称
Rh blood group CcEe antigens
参考文献
  • Zhao FY, et al. (2019) A novel silent rhce allele in chinese population. Transfus Med 29 (6): 430-433.
  • Gaspardi AC, et al. (2016) Clinically relevant rhd-ce genotypes in patients with sickle cell disease and in african brazilian donors. Blood Transfus 14 (5): 449-454.
  • Filosa L, et al. (2019) Identification and characterization of three novel rhce*ce variant alleles affecting rhc (rh4) reactivity. Transfusion 59 (8): 2754-2755.
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