Anti-Thrombopoietin Antibody, Mouse Monoclonal

RRID Number: AB_1960485
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Anti-Thrombopoietin Antibody, Mouse Monoclonal 产品信息

产品名称
Anti-Thrombopoietin Antibody, Mouse Monoclonal
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human Thrombopoietin
免疫原
Human cell-derived rhTHPO (Catalog#10381-H07H)
制备方法
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human THPO (rhTHPO; Catalog#10381-H07H; NP_000451.1; Ser22-Gly353). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
来源
Monoclonal Mouse IgG1 Clone #9H10H8D11
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Thrombopoietin Antibody, Mouse Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Thrombopoietin Antibody, Mouse Monoclonal: 别称

Anti-MGDF Antibody; Anti-MKCSF Antibody; Anti-ML Antibody; Anti-MPLLG Antibody; Anti-THCYT1 Antibody; Anti-TPO Antibody

Thrombopoietin 背景信息

Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.
全称
thrombopoietin
参考文献
  • Ryu T,et al.(2003) Thrombopoietin-producing hepatocellular carcinoma. Intern Med. 42(8): 730-4.
  • Higashihara M,et al. (2003) Thrombopoietin-producing tumor. Intern Med. 42(8): 632-3?
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