Anti-CAMKIV Antibody, Rabbit Polyclonal

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Anti-CAMKIV Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-CAMKIV Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Mouse
特异性
Mouse CAMKIV
免疫原
Recombinant Mouse CAMK4 / CaMKIV protein (Catalog#50838-M20B)
制备方法
Produced in rabbits immunized with purified, recombinant Mouse CAMK4 / CaMKIV (rM CAMK4 / CaMKIV; Catalog#50838-M20B; P08414; Met1-Tyr469). Total IgG was purified by Protein A affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CAMKIV Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CAMKIV Antibody, Rabbit Polyclonal: 别称

Anti-A430110E23Rik Antibody; Anti-AI666733 Antibody; Anti-CaMKIV Antibody; Anti-CaMKIV/Gr Antibody; Anti-D18Bwg0362e Antibody

CAMKIV 背景信息

Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca2+/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca2+ and then apt to combine with the target protein. Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMKⅢ and CaMKⅣ have EF-hand structure.
全称
calcium/calmodulin-dependent protein kinase IV
Related Pathways
  • EGFR Signaling Pathway
    EGFR Signaling Pathway
  • B Cell Receptor Signaling Pathway
    B Cell Receptor Signaling Pathway
  • G Protein-coupled Receptors Signaling
    G Protein-coupled Receptors Signaling
  • T Cell Receptor Signaling Pathway
    T Cell Receptor Signaling Pathway
参考文献
  • Feliciano DM, et al. (2009) Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells. J Biol Chem. 284 (39): 26466-81.
  • Zhao X, et al. (2001). The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking. J Biol Chem. 276 (37): 35042-8.
  • Racioppi L, et al. (2008) Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller.
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