Recombinant Anti-CD14 Antibody (APC), Rabbit Monoclonal

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Recombinant Anti-CD14 Antibody (APC), Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CD14 Antibody (APC), Rabbit Monoclonal
经验证的应用
FCM
交叉反应
Reacts with: Mouse
特异性
Mouse CD14
免疫原
Recombinant Mouse CD14 protein (Catalog#50023-M08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD14 (rM CD14; Catalog#50023-M08H; NP_033971.1; Met1-Pro345) and conjugated with APC under optimum conditions, the unreacted APC was removed.
来源
Monoclonal Rabbit IgG Clone #503
纯化
Protein A
缓冲液
Aqueous solution containing 0.5% BSA and 0.03%ProClin300
偶联物
APC
浓度
2 μl/Test, 0.1 mg/ml
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze !

Recombinant Anti-CD14 Antibody (APC), Rabbit Monoclonal 图片

Profile of anti-CD14 reactivity on Raw264.7 cells analyzed by flow cytometry.

Citation List

Recombinant Anti-CD14 Antibody (APC), Rabbit Monoclonal: 别称

Anti-CD14 Antibody

CD14 背景信息

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
全称
CD14 molecule
Related Pathways
  • NF-kB (NFkB) Pathway
    NF-kB (NFkB) Pathway
参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • SD Wright, et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249 (4975): 1431-3.
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