Recombinant Anti-CD31 Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CD31 Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CD31 Antibody, Rabbit Monoclonal
经验证的应用
ELISA
交叉反应
Reacts with: Mouse
特异性
Mouse CD31
免疫原
Recombinant Mouse CD31 / PECAM-1 Protein (Catalog#50408-M08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD31 / PECAM-1 (rM CD31 / PECAM-1; Catalog#50408-M08H; NP_033868.3; Met1-Lys590).
来源
Monoclonal Rabbit IgG Clone #009
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-CD31 Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-CD31 Antibody, Rabbit Monoclonal: 别称

Anti-C85791 Antibody; Anti-Cd31 Antibody; Anti-Pecam Antibody; Anti-PECAM-1 Antibody

CD31 背景信息

The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
全称
platelet/endothelial cell adhesion molecule 1
参考文献
  • Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.
  • Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.
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