Anti-TNFRSF1A Antibody, Rabbit Polyclonal

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Anti-TNFRSF1A Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-TNFRSF1A Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Mouse
特异性
Mouse TNFRSF1A
免疫原
Recombinant Mouse TNFR1 / CD120a / TNFRSF1A protein (Catalog#50496-M08H)
制备方法
Produced in rabbits immunized with purified, recombinant Mouse TNFR1 / CD120a / TNFRSF1A (rM TNFR1 / CD120a / TNFRSF1A; Catalog#50496-M08H; NP_035739.2; Met 1-Ala 212). TNFR1 / CD120a / TNFRSF1A specific IgG was purified by Mouse TNFR1 / CD120a / TNFRSF1A affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-TNFRSF1A Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-TNFRSF1A Antibody, Rabbit Polyclonal: 别称

Anti-CD120a Antibody; Anti-FPF Antibody; Anti-p55 Antibody; Anti-p55-R Antibody; Anti-TNF-alphaR1 Antibody; Anti-TNF-R Antibody; Anti-TNF-R-I Antibody; Anti-TNF-R1 Antibody; Anti-TNF-R55 Antibody; Anti-TNFalpha-R1 Antibody; Anti-TNFAR Antibody; Anti-Tnfr-2 Antibody; Anti-Tnfr1 Antibody; Anti-TNFR60 Antibody; Anti-TNFRI Antibody; Anti-TNFRp55 Antibody

TNFRSF1A 背景信息

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
全称
tumor necrosis factor receptor superfamily member 1A
研究领域
Related Pathways
  • Death Receptor Signaling
    Death Receptor Signaling
  • NF-kB (NFkB) Pathway
    NF-kB (NFkB) Pathway
  • TNF Signaling
    TNF Signaling
参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
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